Anti-DCXR抗体(ab11800)

概述

  • 产品名称Anti-DCXR抗体
    参阅全部 DCXR 一抗
  • 描述
    山羊多克隆抗体to DCXR
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Guinea pig, Hamster
  • 免疫原

    Synthetic peptide:

    GSTLPVEGGFWAC

    , corresponding to amino acids 232-244 of Human DCXR.

  • 阳性对照
    • Hela and Human Kidney lysates.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab11800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
ELISA
WB
  • 应用说明ELISA: 1/32000.
    WB: Use at a concentration of 0.1 - 0.5 µg/ml. Detects a band of approximately 28 kDa in Hela and Human Kidney lysates.
    IHC-P: Use at a concentration of 1 - 2 µg/ml. In paraffin embedded Human Kidney, stains membrane / cytoplasm in epithelial cells of renal glomeruli and tubules.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
    • 组织特异性Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
    • 疾病相关Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
    • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    • 细胞定位Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Carbonyl reductase 2 antibody
      • Carbonyl reductase II antibody
      • DCR antibody
      • Dcxr antibody
      • DCXR_HUMAN antibody
      • Dicarbonyl L xylulose reductase antibody
      • Dicarbonyl/ L xylulose reductase antibody
      • Dicarbonyl/L-xylulose reductase antibody
      • HCR2 antibody
      • HCRII antibody
      • Human carbonyl reductase 2 antibody
      • kiDCR antibody
      • Kidney dicarbonyl reductase antibody
      • L xylulose reductase antibody
      • L-xylulose reductase antibody
      • P34H antibody
      • PNTSU antibody
      • SDR20C1 antibody
      • Short chain dehydrogenase/reductase family 20C member 1 antibody
      • Sperm surface protein P34H antibody
      • XR antibody
      see all

    Anti-DCXR antibody 图像

    • Ab11800 staining (0.1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
    • Ab11800 (1ug/ml) staining human DCXR in human kidney by immunohistochemistry using paraffin embedded tissue.

      Microwaved antigen retrieval with citrate buffer, pH6, HRP-staining.

    Anti-DCXR antibody (ab11800)参考文献

    ab11800 has not yet been referenced specifically in any publications.

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