概述

  • 产品名称
  • 描述
    兔多克隆抗体to DCTN4
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 of Human DCTN4 (NP_057305).

  • 阳性对照
    • Human fetal muscle lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab98098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Optimal concentration of antibody depends the protein level in a given sample. Our recommended concentrations are the starting point for general use. Customers are advised have to do a series of titration tests to determine optimal concentration. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
  • 序列相似性
    Belongs to the dynactin subunit 4 family.
  • 细胞定位
    Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution, suggesting that this polypeptide may be targeted to the nucleus at very high expression levels.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DCTN 4 antibody
    • Dctn4 antibody
    • DCTN4_HUMAN antibody
    • Dynactin 4 (p62) antibody
    • Dynactin 4 antibody
    • Dynactin p62 subunit antibody
    • Dynactin subunit 4 antibody
    • Dynactin subunit p62 antibody
    • Dynactin4 antibody
    • p62 antibody
    see all

Anti-DCTN4 antibody 图像



  • Predicted band size : 52 kDa
    Western blot analysis of Human fetal brain tissue lysate labeling DCTN4 with ab98098 at 1.0µg/ml.
  • Anti-DCTN4 antibody (ab98098) at 1 µg/ml + Human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 52 kDa
    Gel concentration: 12%

实验方案

Anti-DCTN4 antibody (ab98098)参考文献

ab98098 has not yet been referenced specifically in any publications.

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