概述

描述

  • 性质Synthetic

技术指标

Our Abpromise guarantee covers the use of ab8379 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

常规信息

  • 别名
    • CD 264
    • CD264
    • DcR 2
    • DcR2
    • Decoy receptor 2
    • Decoy with truncated death domain
    • OTTHUMP00000123528
    • TNF receptor related receptor for TRAIL
    • TNF related apoptosis inducing ligand receptor 4
    • TNF-related apoptosis-inducing ligand receptor 4
    • TNFRSF 10D
    • TNFRSF10D
    • TR10D_HUMAN
    • TRAIL R4
    • TRAIL receptor 4
    • TRAIL receptor with a truncated death domain
    • TRAIL-R4
    • TRAILR4
    • TRUNDD
    • Tumor necrosis factor receptor superfamily member 10D
    • Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
    see all
  • 功能Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
  • 组织特异性Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
  • 序列相似性Contains 1 death domain.
    Contains 3 TNFR-Cys repeats.
  • 细胞定位Membrane.
  • Information by UniProt

DcR2 peptide (ab8379)参考文献

ab8379 has not yet been referenced specifically in any publications.

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