概述

  • 产品名称Anti-DcR2抗体
    参阅全部 DcR2 一抗
  • 描述
    兔多克隆抗体to DcR2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to a region within C terminal amino acids 253-283 of Human DcR2 (NP_003831.20).

  • 阳性对照
    • CEM cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab116450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.

靶标

  • 功能Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
  • 组织特异性Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
  • 序列相似性Contains 1 death domain.
    Contains 3 TNFR-Cys repeats.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 264 antibody
    • CD264 antibody
    • DcR 2 antibody
    • DcR2 antibody
    • Decoy receptor 2 antibody
    • Decoy with truncated death domain antibody
    • OTTHUMP00000123528 antibody
    • TNF receptor related receptor for TRAIL antibody
    • TNF related apoptosis inducing ligand receptor 4 antibody
    • TNF-related apoptosis-inducing ligand receptor 4 antibody
    • TNFRSF 10D antibody
    • TNFRSF10D antibody
    • TR10D_HUMAN antibody
    • TRAIL R4 antibody
    • TRAIL receptor 4 antibody
    • TRAIL receptor with a truncated death domain antibody
    • TRAIL-R4 antibody
    • TRAILR4 antibody
    • TRUNDD antibody
    • Tumor necrosis factor receptor superfamily member 10D antibody
    • Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain antibody
    see all

Anti-DcR2 antibody 图像

  • Anti-DcR2 antibody (ab116450) at 1/100 dilution + CEM cell line lysates at 35 µg

    Predicted band size : 42 kDa

Anti-DcR2 antibody (ab116450)参考文献

ab116450 has not yet been referenced specifically in any publications.

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