概述

  • 产品名称Anti-DBF4B抗体
    参阅全部 DBF4B 一抗
  • 描述
    小鼠多克隆抗体to DBF4B
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human DBF4B protein (NP_079380.1)

  • 阳性对照
    • DBF4B transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69154 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: Isoform 4, 18 kDa; Isoform 1, 67 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle.
    • 组织特异性Widely expressed. Highly expressed in testis.
    • 序列相似性Contains 1 BRCT domain.
      Contains 1 DBF4-type zinc finger.
    • 发展阶段Increases as cells enter in S phase through G2/M phase. The protein has a short half-life (at protein level).
    • 翻译后修饰Phosphorylated.
    • 细胞定位Nucleus. Predominantly found in soluble fraction but not in the chromatin-bound fraction.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Activator of S phase kinase like protein 1 antibody
      • Activator of S phase kinase-like protein 1 antibody
      • ASK like protein 1 antibody
      • ASK-like protein 1 antibody
      • ASKL1 antibody
      • chifb antibody
      • Chiffon homolog B antibody
      • DBF 4B antibody
      • DBF4 homolog B (S. cerevisiae) antibody
      • DBF4 homolog B antibody
      • Dbf4 related factor 1 antibody
      • Dbf4-related factor 1 antibody
      • dbf4b antibody
      • DBF4B_HUMAN antibody
      • DRF1 antibody
      • FLJ13087 antibody
      • MGC15009 antibody
      • Protein DBF4 homolog B antibody
      • ZDBF1B antibody
      • Zinc finger DBF type containing 1B antibody
      see all

    Anti-DBF4B antibody 图像

    • All lanes : Anti-DBF4B antibody (ab69154) at 1/500 dilution

      Lane 1 : DBF4B transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 18 kDa
      Observed band size : 18 kDa

    Anti-DBF4B antibody (ab69154)参考文献

    ab69154 has not yet been referenced specifically in any publications.

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