产品名称 Anti-DBF4抗体[EPR5635] 参阅全部 DBF4 一抗
兔单克隆抗体[EPR5635] to DBF4
WB more details 不适用于:
Flow Cyt,ICC/IF,IHC-P or IP
Synthetic peptide corresponding to residues in Human DBF4 protein (Q9UBU7).
PC-3, Jurkat, SW480, and HepG2 cell lysates.
This product is a recombinant rabbit monoclonal antibody.
Produced using Abcam’s RabMAb
® technology. RabMAb ® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
存放说明 Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
K D = 2.49 x 10
Learn more about K D
存储溶液 PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
纯度 Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/10000 - 1/50000. Predicted molecular weight: 77 kDa.
应用说明 Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
功能 Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
组织特异性 Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
序列相似性 Contains 2 BRCT domains. Contains 1 DBF4-type zinc finger.
翻译后修饰 Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
Activator of S phase kinase antibody
Anti-DBF4 antibody [EPR5635] 图像
Anti-DBF4 antibody [EPR5635] (ab124707)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"