概述

  • 产品名称Anti-DBF4抗体
    参阅全部 DBF4 一抗
  • 描述
    小鼠单克隆抗体to DBF4
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: NSGAMRIHSK GHFQGGIQVK NEKNRPSLKS LKTDNRPEKS KCKPLWGKVF YLDLPSVTIS EKLQKDIKDL GGRVEEFLSK DISYLISNKK EAKFAQT, corresponding to amino acids 2-99 of Human DBF4

性能

应用

Our Abpromise guarantee covers the use of ab56813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
    • 组织特异性Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
    • 序列相似性Contains 2 BRCT domains.
      Contains 1 DBF4-type zinc finger.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Activator of S phase kinase antibody
      • ASK antibody
      • CHIF antibody
      • Chiffon homolog A antibody
      • DBF4 antibody
      • DBF4 homolog (S. cerevisiae) antibody
      • DBF4 homolog antibody
      • DBF4 type zinc finger containing protein 1 antibody
      • DBF4 zinc finger A antibody
      • DBF4 zinc finger antibody
      • DBF4, S. cerevisiae, homolog of antibody
      • DBF4-type zinc finger-containing protein 1 antibody
      • DBF4A antibody
      • DBF4A_HUMAN antibody
      • Dumbbell former 4, S. cerevisiae, homolog of antibody
      • OTTHUMP00000161661 antibody
      • Protein DBF4 homolog A antibody
      • ZDBF1 antibody
      • Zinc finger, DBF-type containing 1 antibody
      see all

    Anti-DBF4 antibody 图像

    • BDF4 antibody (ab56813) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human spleen.
    • Western blot against tagged recombinant protein immunogen using ab56813 BDF4 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    Anti-DBF4 antibody (ab56813)参考文献

    ab56813 has not yet been referenced specifically in any publications.

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