The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-DAZL antibody (ab40848)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
DAZ like autosomal
Deleted in azoospermia like
Deleted in azoospermia like 1
Deleted in azoospermia like autosomal
Deleted in azoospermia-like
Deleted in azoospermia-like 1
Germline specific RNA binding protein
Spermatogenesis gene on the Y like autosomal
SPGY like autosomal
功能RNA-binding protein, which is essential for gametogenesis. Plays a central role during spermatogenesis. May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts.
序列相似性Belongs to the RRM DAZ family. Contains 1 DAZ-like domain. Contains 1 RRM (RNA recognition motif) domain.
结构域The DAZ-like domain mediates the interaction with DAZAP1 and DAZAP2.
细胞定位Cytoplasm. Nucleus. Predominantly cytoplasmic (By similarity). Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.