概述

  • 产品名称Anti-DAZ3抗体
    参阅全部 DAZ3 一抗
  • 描述
    兔多克隆抗体to DAZ3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Guinea pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 216-265 (

    FPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFP

    ) of Human DAZ3 (NP_065097).

  • 阳性对照
    • OVCAR-3 cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab94695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
  • 组织特异性Testis specific.
  • 疾病相关Spermatogenic failure Y-linked 2
  • 序列相似性Belongs to the RRM DAZ family.
    Contains 12 DAZ-like domains.
    Contains 1 RRM (RNA recognition motif) domain.
  • 结构域The DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.
  • 细胞定位Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DAZ3 antibody
    • DAZ3_HUMAN antibody
    • deleted in azoospermia 3 antibody
    • Deleted in azoospermia protein 3 antibody
    • MGC126441 antibody
    • pDP1679 antibody
    see all

Anti-DAZ3 antibody 图像

  • Anti-DAZ3 antibody (ab94695) at 1 µg/ml + OVCAR3 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 55 kDa

Anti-DAZ3 antibody (ab94695)参考文献

ab94695 has not yet been referenced specifically in any publications.

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