概述

  • 产品名称Anti-DAZ2抗体
    参阅全部 DAZ2 一抗
  • 描述
    兔多克隆抗体to DAZ2
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 1 - 207 of Human DAZ2 (NP_065096).

  • 阳性对照
    • WB: 293T, A431, HeLa, MOLT4 and Raji cell lysate IF: HeLa cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab97772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 63 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
  • 组织特异性Testis specific.
  • 疾病相关Defects in DAZ2 may be a cause of spermatogenic failure Y-linked type 2 (SPGFY2) [MIM:415000]. It is a disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. Note=AZFc deletions in the Yq11.23 region including the DAZ genes are the most common known genetic cause of human male infertility.
  • 序列相似性Belongs to the RRM DAZ family.
    Contains 15 DAZ-like domains.
    Contains 1 RRM (RNA recognition motif) domain.
  • 结构域The DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.
  • 细胞定位Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DAZ2 antibody
    • DAZ2_HUMAN antibody
    • DAZ3 antibody
    • Deleted in azoospermia 2 antibody
    • Deleted in azoospermia protein 2 antibody
    • Deleted in azoospermia protein 3 antibody
    • MGC126442 antibody
    • pDP1678 antibody
    see all

Anti-DAZ2 antibody 图像

  • Anti-DAZ2 antibody (ab97772) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

    Predicted band size : 63 kDa
  • ab97772, at a 1/200 dilution, staining DAZ2 in paraformaldehyde-fixed HeLa cells by Immunofluorescence analysis. Right image is merged with a DNA probe.

Anti-DAZ2 antibody (ab97772)参考文献

ab97772 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab97772.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"