Anti-DARC抗体(ab124648)

概述

  • 产品名称Anti-DARC抗体
    参阅全部 DARC 一抗
  • 描述
    兔多克隆抗体to DARC
  • 经测试应用适用于: ELISA, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide from the N terminus of Human DARC.

  • 阳性对照
    • Human thymus tissue; A549 cells.

性能

应用

Our Abpromise guarantee covers the use of ab124648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/40000.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF 1/100 - 1/500.

靶标

  • 功能Non-specific receptor for many chemokines such as IL-8, GRO, RANTES, MCP-1 and TARC. It is also the receptor for the human malaria parasites Plasmodium vivax and Plasmodium knowlesi.
  • 组织特异性Found in adult kidney, adult spleen, bone marrow and fetal liver. In particular, it is expressed along postcapillary venules throughout the body, except in the adult liver. Erythroid cells and postcapillary venule endothelium are the principle tissues expressing duffy. Fy(-A-B) individuals do not express duffy in the bone marrow, however they do, in postcapillary venule endothelium.
  • 序列相似性Belongs to the G-protein coupled receptor Duffy family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCBP1 antibody
    • CD234 antibody
    • DARC antibody
    • Dfy antibody
    • Duffy antigen/chemokine receptor antibody
    • duffy blood group antibody
    • Duffy blood group antigen antibody
    • Duffy blood group chemokine receptor antibody
    • DUFFY_HUMAN antibody
    • FY antibody
    • Fy glycoprotein antibody
    • Glycoprotein D antibody
    • GPD antibody
    • GpFy antibody
    • Plasmodium vivax receptor antibody
    • WBCQ1 antibody
    see all

Anti-DARC antibody 图像

  • ab124648, at 5µg/ml, staining DARC in Formalin-fixed, Paraffin-embedded Human Thymus vessel tissue by Immunohistochemistry.
  • ab124648, at 1/100 dilution, staining DARC in A549 cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.

Anti-DARC antibody (ab124648)参考文献

ab124648 has not yet been referenced specifically in any publications.

Product Wall



The immunogenic peptide does not overlap with the FY6 aa#19-25 region. That being said, the amino range of the immunogen is aa#30-60 of human DARC with acc#Q16570 (http://www.uniprot.org/uniprot/Q16570), and aa#42 is in that range.

Unfortunately, the lab will not release the sequence of the peptide used to generate this antibody. They did tell me that the immunogenic peptide does not overlap with the region described you have described.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"