概述

  • 产品名称Anti-DAPP1抗体
    参阅全部 DAPP1 一抗
  • 描述
    山羊多克隆抗体to DAPP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Peptide with sequence C-

    KLSQIRKQLNQGE

    , corresponding to C terminal amino acids 257-269 from the internal region (near C Terminus) of Human DAPP1 (NP_055210.2)

  • 阳性对照
    • Transfected HEK293 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 32 kDa).

靶标

  • 功能May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
  • 组织特异性Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
  • 序列相似性Contains 1 PH domain.
    Contains 1 SH2 domain.
  • 翻译后修饰Phosphorylated on tyrosine residues.
  • 细胞定位Cytoplasm. Membrane. Membrane-associated after cell stimulation leading to its translocation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B cell adapter molecule of 32 kDa antibody
    • B lymphocyte adapter protein Bam32 antibody
    • B-cell adapter molecule of 32 kDa antibody
    • BAM32 antibody
    • DAPP1 antibody
    • DAPP1_HUMAN antibody
    • DKFZp667E0716 antibody
    • Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide antibody
    • Dual adaptor of phosphotyrosine and 3 phosphoinositides antibody
    • hDAPP1 antibody
    see all

Anti-DAPP1 antibody 图像

  • Lane 1 : Anti-DAPP1 antibody (ab123498) at 0.1 µg/ml
    Lane 2 : Anti-DAPP1 antibody (ab123498) at 1 mg/ml
    Lane 3 : Anti-DYKDDDDK Tag antibody at 1/3000 dilution

    Lane 1 : HEK293 lysate in RIPA buffer over expressing Human DAPP1 with DYKDDDDK tag
    Lane 2 : Mock-transfected HEK293
    Lane 3 : HEK293 lysate in RIPA buffer over expressing Human DAPP1 with DYKDDDDK tag


    Predicted band size : 32 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)

Anti-DAPP1 antibody (ab123498)参考文献

ab123498 has not yet been referenced specifically in any publications.

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