概述

  • 产品名称Anti-DAP5抗体
    参阅全部 DAP5 一抗
  • 描述
    兔多克隆抗体to DAP5
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus)
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 125-175 of Human DAP5 (NP_001409.1).

  • 阳性对照
    • Human Non-Small Cell Lung Cancer and Human Ovarian Carcinoma tissues.

性能

应用

Our Abpromise guarantee covers the use of ab117804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.
ICC/IF 1/100 - 1/500.

靶标

  • 功能Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
  • 组织特异性Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.
  • 序列相似性Belongs to the eIF4G family.
    Contains 1 MI domain.
    Contains 1 MIF4G domain.
    Contains 1 W2 domain.
  • 翻译后修饰Phosphorylation; hyperphosphorylated during mitosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DAP-5 antibody
    • Death associated protein 5 antibody
    • Death-associated protein 5 antibody
    • eIF-4-gamma 2 antibody
    • eIF-4G 2 antibody
    • eIF4G 2 antibody
    • EIF4G2 antibody
    • Eukaryotic translation initiation factor 4 gamma 2 antibody
    • IF4G2_HUMAN antibody
    • Nat1 antibody
    • Novel APOBEC-1 target 1 antibody
    • p97 antibody
    • Translation repressor NAT1 antibody
    • Translation repressor NAT1 antibody
    see all

Anti-DAP5 antibody 图像

  • ab117804 at 1/250 dilution staining DAP5 in Formalin-fixed, Paraffin-embedded Human ovarian carcinoma tissue by Immunohistochemistry.
    Detection: DAB staining.
  • ab117804 at 1/100 dilution staining DAP5 in Formalin-fixed Paraffin-embedded Human ovarian carcinoma tissue by Immunofluorescence. Detection:Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1/100.

Anti-DAP5 antibody (ab117804)参考文献

ab117804 has not yet been referenced specifically in any publications.

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