Anti-DAP12抗体(ab25098)
Key features and details
- Rabbit polyclonal to DAP12
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-DAP12抗体
参阅全部 DAP12 一抗 -
描述
兔多克隆抗体to DAP12 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
E. coli expressed recombinant fragment:
QSDNYPGCECSSV
, corresponding to amino acids 28/40 of Rat DAP12 -
阳性对照
- WB: Day 8 rat tubular interstitial nephritis model.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 99.9% PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25098于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000. Predicted molecular weight: 13 kDa.
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说明 |
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WB
1/1000. Predicted molecular weight: 13 kDa. |
靶标
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功能
Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. -
组织特异性
Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Expressed in hematological cells and tissues such as peripheral blood leukocytes and spleen. Also found in bone marrow, lymph nodes, placenta, lung and liver. Expressed at lower levels in different parts of the brain especially in the basal ganglia and corpus callosum. -
疾病相关
Defects in TYROBP are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) [MIM:221770]; also called presenile dementia with bone cysts or Nasu-Hakola disease (NHD). PLOSL is a recessively inherited disease characterized by a combination of psychotic symptoms rapidly progressing to presenile dementia and bone cysts restricted to wrists and ankles. PLOSL has a global distribution, although most of the patients have been diagnosed in Finland and Japan, with an estimated population prevalence of 2x10(-6) in the Finns. -
序列相似性
Belongs to the TYROBP family. -
翻译后修饰
Tyrosine phosphorylated. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 361537 Rat
- SwissProt: Q6X9T7 Rat
- Unigene: 11534 Rat
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别名
- DAP 12 antibody
- DAP12 antibody
- DNAX activation protein 12 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab25098 尚未被引用在任何文献中。