概述

  • 产品名称
    DAMGO
  • 描述
    Potent and selective μ opioid receptor agonist
  • 生物学描述
    Potent and selective μ opioid receptor agonist (Ki values are 2.0, >1000 and >1000 nM for opioid receptor subtypes μ, κ and δ, respectively). Partial central activity following systemic administration. Antinociceptive.
  • 纯度
    > 95%

性能

文献

This product has been referenced in:
  • Lowery JJ  et al. Glycosylation improves the central effects of DAMGO. Chem Biol Drug Des 69:41-7 (2007). Read more (PubMed: 17313456) »
  • Shin MS & Helmstetter FJ Antinociception following application of DAMGO to the basolateral amygdala results from a direct interaction of DAMGO with Mu opioid receptors in the amygdala. Brain Res 1064:56-65 (2005). Read more (PubMed: 16289487) »
  • Raynor K  et al. Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol 45:330-4 (1994). Read more (PubMed: 8114680) »

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