RabMAb

Anti-Dab1抗体[EP2248Y] (ab68461)

概述

  • 产品名称Anti-Dab1抗体[EP2248Y]
    参阅全部 Dab1 一抗
  • 描述
    兔单克隆抗体[EP2248Y] to Dab1
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC/IF,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    A synthetic peptide corresponding to residues surrounding serine 491 of human Dab1.

  • 阳性对照
    • Rat brain lysate.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Human: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab68461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/1000 - 1/2000. Detects a band of approximately 70 kDa (predicted molecular weight: 67 kDa).

    Is unsuitable for Flow Cyt, ICC/IF, IHC-P or IP.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Adapter molecule functioning in neural development. May regulate SIAH1 activity.
    • 序列相似性Contains 1 PID domain.
    • 结构域The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
    • 翻译后修饰Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Dab 1 antibody
      • Dab reelin signal transducer 1 antibody
      • Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
      • Dab1 antibody
      • DAB1_HUMAN antibody
      • Disabled homolog 1 antibody
      • Disabled homolog 1 Drosophila antibody
      • Scm antibody
      • Scr antibody
      • Scrambler antibody
      • Yot antibody
      • Yotari antibody
      see all

    Anti-Dab1 antibody [EP2248Y] 图像

    • Anti-Dab1 antibody [EP2248Y] (ab68461) at 1/2000 dilution + Rat brain lysate at 10 µg

      Secondary
      HRP conjugated Goat anti Rabbit. at 1/2000 dilution

      Predicted band size : 67 kDa
      Observed band size : 70 kDa (why is the actual band size different from the predicted?)

    Anti-Dab1 antibody [EP2248Y] (ab68461)参考文献

    ab68461 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"