Anti-DAAM1抗体- C-terminal (ab71499)

概述

  • 产品名称Anti-DAAM1抗体- C-terminal
    参阅全部 DAAM1 一抗
  • 描述
    兔多克隆抗体to DAAM1 - C-terminal
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the N-terminal region of human DAAM1, conjugated to KLH.

  • 阳性对照
    • Paraffin embedded human brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab71499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 123 kDa (predicted molecular weight: 123 kDa).
IHC-P 1/10 - 1/50.
ELISA 1/1000.

靶标

  • 相关性DAAM1 (Dishevelled associated activator of morphogenesis 1) is a diaphanous-related formin which binds to dishevelled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex assembly. It is an essential component of noncanonical Wnt signaling. DAAM1 also communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system. DAAM1 may be a coordinator of endocytosis and cytoskeletal remodeling.
  • 细胞定位Cytoplasmic. Note: Perinuclear.
  • 数据库链接
  • 别名
    • DAAM 1 antibody
    • Dishevelled associated activator of morphogenesis 1 antibody
    • FLJ41657 antibody
    • KIAA0666 antibody

Anti-DAAM1 antibody - C-terminal 图像

  • All lanes : Anti-DAAM1 antibody - C-terminal (ab71499) at 1/100 dilution

    Lane 1 : Non-transfected 293 cell lysate
    Lane 2 : DAAM1 transfected 293 cell lysate

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 123 kDa
    Observed band size : 123 kDa
    Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemical analysis of paraffin embedded human brain tissue using ab71499 at 1/10 dilution.

Anti-DAAM1 antibody - C-terminal (ab71499)参考文献

ab71499 has not yet been referenced specifically in any publications.

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