概述

  • 产品名称
  • 描述
    小鼠单克隆抗体to DAAM1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-111 of Human DAAM1

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

应用

Our Abpromise guarantee covers the use of ab56951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明
    WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性
      DAAM1 (Dishevelled associated activator of morphogenesis 1) is a diaphanous-related formin which binds to dishevelled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex assembly. It is an essential component of noncanonical Wnt signaling. DAAM1 also communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system. DAAM1 may be a coordinator of endocytosis and cytoskeletal remodeling.
    • 细胞定位
      Cytoplasmic. Note: Perinuclear.
    • 数据库链接
    • 别名
      • DAAM 1 antibody
      • Dishevelled associated activator of morphogenesis 1 antibody
      • FLJ41657 antibody
      • KIAA0666 antibody

    Anti-DAAM1 antibody 图像



    • Predicted band size : 123 kDa
      DAAM1 antibody (ab56951) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    实验方案

    Anti-DAAM1 antibody (ab56951)参考文献

    This product has been referenced in:
    • Luo W  et al. Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network. PLoS One 11:e0163915 (2016). WB ; Human . Read more (PubMed: 27760153) »
    • Lynch J  et al. Metastasis Suppressor microRNA-335 Targets the Formin Family of Actin Nucleators. PLoS One 8:e78428 (2013). WB ; Human . Read more (PubMed: 24223803) »

    See all 4 Publications for this product

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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