Anti-Cytomegalovirus pp65抗体[3A12] (ab6503)

概述

  • 产品名称Anti-Cytomegalovirus pp65抗体[3A12]
    参阅全部 Cytomegalovirus pp65 一抗
  • 描述
    小鼠单克隆抗体[3A12] to Cytomegalovirus pp65
  • 特异性Cytomegalovirus pp65 (Lower Matrix Protein).
  • 经测试应用适用于: WB, ICC/IFmore details
  • 免疫原

    Cytomegalovirus

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Phosphate buffered saline
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号3A12
  • 骨髓瘤NS1/1-Ag4-1
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab6503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/16000.
ICC/IF 1/3200.

靶标

  • 相关性Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein and is the most abundant of the late antigens.
  • 别名
    • 65 kDa matrix phosphoprotein antibody
    • 65 kDa phosphoprotein antibody
    • Tegument protein pp65 antibody
    • Tegument protein UL83 antibody

Anti-Cytomegalovirus pp65 antibody [3A12] (ab6503)参考文献

This product has been referenced in:
  • Zimmermann A  et al. Checks and balances between human cytomegalovirus replication and indoleamine-2,3-dioxygenase. J Gen Virol 95:659-70 (2014). WB . Read more (PubMed: 24337170) »
  • McFarlane S  et al. Early induction of autophagy in human fibroblasts after infection with human cytomegalovirus or herpes simplex virus 1. J Virol 85:4212-21 (2011). WB . Read more (PubMed: 21325419) »

See all 4 Publications for this product

Product Wall

Thank you for your inquiry. As you may have seen already, we have a number of HCMV pp65 antibodies available in our catalog (such as ab6503, ab8250, ab31624, ab49214, ab53489). These were raised against the pp65 protein, however, unfortunately the ...

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I put your question forward to the originator but they said that the epitope has not been characterised so they do not have the information. I am sorry we cannot be of help to you.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"