Anti-Cytomegalovirus AD169 Late antigen抗体[QB1/06] (ab49211)

概述

  • 产品名称Anti-Cytomegalovirus AD169 Late antigen抗体[QB1/06]
  • 描述
    小鼠单克隆抗体[QB1/06] to Cytomegalovirus AD169 Late antigen
  • 经测试应用适用于: IHC-Fr, IHC-Pmore details
    不适用于: WB
  • 种属反应性
    Reacts with Cytomegalovirus. Not yet tested in other species.
  • 免疫原

    Partially purified extracts of human embryonic lung fibroblasts infected with CMV strain AD169

  • 阳性对照
    • CMV infected tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: Tissue culture supernatant
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号QB1/06
  • 骨髓瘤NS0
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab49211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr
IHC-P
  • 应用说明IHC-Fr: 1/50.
    IHC-P: 1/50. Heat mediated antigen retrieval is recommended before commencing with IHC staining protocol. Use 60 minutes primary antibody incubation at 25oC and standard ABC technique.


    Is unsuitable for WB.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Cytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. CMV strain AD169 is a laboratory-adapted strain. It appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.
    • 别名
      • HCMV antibody
      • HHV 5 antibody
      • Human Herpesvirus 5 antibody
      • Tegument protein antibody

    Anti-Cytomegalovirus AD169 Late antigen antibody [QB1/06] (ab49211)参考文献

    ab49211 has not yet been referenced specifically in any publications.

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