Anti-Cytomegalovirus AD169抗体(ab31991)

概述

  • 产品名称Anti-Cytomegalovirus AD169抗体
    参阅全部 Cytomegalovirus AD169 一抗
  • 描述
    山羊多克隆抗体to Cytomegalovirus AD169
  • 特异性ab31991 recognizes Cytomegalovirus, Strain AD 169. It shows predominant reactivity to glycoprotein B (gB), and does not crossreact with HSV and V2V by Immunofluorescence. Negative vs Hep2 cells and human fibroblasts by Indirect Immunofluorescence.
  • 经测试应用适用于: ELISA, Conjugation, ICC, WB, ICC/IFmore details
  • 种属反应性
    Cytomegalovirus, Strain AD 169.
  • 免疫原

    Purified virons of Cytomegalovirus, Strain AD 169.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.1% Sodium Azide.
    Constituents: PBS.
  • Concentration information loading...
  • 纯度>95% by SDS-PAGE
  • 纯化说明ab31991 was purified by sodium sulfate precipitation and ion exchange chromatography (> 95%).
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab31991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
Conjugation
ICC
WB
ICC/IF
  • 应用说明Conjugation: Use at an assay dependent dilution.
    ELISA: Use at an assay dependent dilution.
    ICC: Use at an assay dependent dilution.
    IF (indirect): 1/2000.
    WB: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Cytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. Cytomegalovirus strain AD169 is a laboratory-adapted strain and appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.
    • 别名
      • HCMV antibody
      • HHV5 antibody
      • Human Herpesvirus 5 antibody
      • UL55 (strain AD169) antibody

    Anti-Cytomegalovirus AD169 antibody (ab31991)参考文献

    ab31991 has not yet been referenced specifically in any publications.

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