Anti-Cytokeratin 8抗体[SB37b] (FITC) (ab87010)

概述

  • 产品名称Anti-Cytokeratin 8抗体[SB37b] (FITC)
    参阅全部 Cytokeratin 8 一抗
  • 描述
    小鼠单克隆抗体[SB37b] to Cytokeratin 8 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性ab87010 reacts specifically with cytokeratin 8 and the recombinant C terminal of cytokeratin 8.
  • 经测试应用适用于: ICC/IF, ELISA, WB, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant C terminal fragment of Cytokeratin 8

  • 阳性对照
    • HT29 and HCC38 cells. HT29 and HCC38 cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab87010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 54 kDa.
IHC-Fr Use a concentration of 10 µg/ml.

靶标

  • 功能Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
  • 组织特异性Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
  • 疾病相关Cirrhosis
  • 序列相似性Belongs to the intermediate filament family.
  • 翻译后修饰Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
    O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
    O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
  • 细胞定位Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CARD2 antibody
    • CK 8 antibody
    • CK-8 antibody
    • CK8 antibody
    • CYK8 antibody
    • CYKER antibody
    • Cytokeratin endo A antibody
    • Cytokeratin-8 antibody
    • DreK8 antibody
    • EndoA antibody
    • K2C8 antibody
    • K2C8_HUMAN antibody
    • K8 antibody
    • Keratin 8 antibody
    • Keratin type II cytoskeletal 8 antibody
    • Keratin, type II cytoskeletal 8 antibody
    • Keratin-8 antibody
    • KO antibody
    • Krt 2.8 antibody
    • KRT8 antibody
    • MGC118110 antibody
    • MGC174782 antibody
    • MGC53564 antibody
    • MGC85764 antibody
    • sb:cb186 antibody
    • Type-II keratin Kb8 antibody
    see all

Anti-Cytokeratin 8 antibody [SB37b] (FITC) 图像

  • ab87010, at 10 µg/ml, staining Cytokeratin 8 in frozen sections of the HCC38 pancreatic carcinoma cell line by Immunohistochemistry. Positive cells are viewed by fluorescence microscopy.

Anti-Cytokeratin 8 antibody [SB37b] (FITC) (ab87010)参考文献

ab87010 has not yet been referenced specifically in any publications.

Product Wall


The source of the antibody considers the F:P ratio to be proprietary.
They have not measured the isoelectric point (pI) of this particular antibody, but some studies indicate that most mouse monoclonal antibodies fall in the range of 6.4 - 7.6...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"