Anti-Cytokeratin 6a抗体(ab52869)

概述

  • 产品名称Anti-Cytokeratin 6a抗体
    参阅全部 Cytokeratin 6a 一抗
  • 描述
    兔多克隆抗体to Cytokeratin 6a
  • 经测试应用适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Human
    不与反应: Rat
  • 免疫原

    Synthetic peptide within Human Cytokeratin 6a aa 1-100 (N terminal). The exact sequence is proprietary.

  • 阳性对照
    • WB: A431 cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab52869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 60 kDa).
Flow Cyt 1/15. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

靶标

  • 组织特异性Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
  • 疾病相关Defects in KRT6A are a cause of pachyonychia congenita type 1 (PC1) [MIM:167200]; also known as Jadassohn-Lewandowsky syndrome. PC1 is an autosomal dominant ectodermal dysplasia characterized by hypertrophic nail dystrophy resulting in onchyogryposis (thickening and increase in curvature of the nail), palmoplantar keratoderma, follicular hyperkeratosis, and oral leukokeratosis. Hyperhidrosis of the hands and feet is usually present.
  • 序列相似性Belongs to the intermediate filament family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CK-6A antibody
    • CK-6D antibody
    • CK6A antibody
    • CK6C antibody
    • CK6D antibody
    • Cytokeratin-6A antibody
    • Cytokeratin-6D antibody
    • K2C6A_HUMAN antibody
    • K6A antibody
    • K6C antibody
    • K6D antibody
    • keratin 6A antibody
    • Keratin antibody
    • Keratin, type II cytoskeletal 6A antibody
    • Keratin-6A antibody
    • Krt6a antibody
    • KRT6C antibody
    • KRT6D antibody
    • type II cytoskeletal 6A antibody
    • Type-II keratin Kb6 antibody
    see all

Anti-Cytokeratin 6a antibody 图像

  • Anti-Cytokeratin 6a antibody (ab52869) at 1/500 dilution + A431 cell lysate at 10 µg

    Secondary
    Goat anti-rabbit HRP at 1/2000 dilution

    Predicted band size : 60 kDa
    Observed band size : 56 kDa (why is the actual band size different from the predicted?)

Anti-Cytokeratin 6a antibody (ab52869)参考文献

ab52869 has not yet been referenced specifically in any publications.

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