概述

  • 产品名称
    Anti-Cytokeratin 5 + 14抗体[16.4]
    参阅全部 Cytokeratin 5 + 14 一抗
  • 描述
    小鼠单克隆抗体[16.4] to Cytokeratin 5 + 14
  • 经测试应用
    适用于: ICC/IF, IHC-Fr, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue/ cell preparation (cytokeratin enriched extract of feline tongue epithelium).

性能

应用

Our Abpromise guarantee covers the use of ab16570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF
IHC-Fr
WB
  • 应用说明
    ICC/IF: Use at an assay dependent dilution (from PubMed: 17361080)
    IHC-Fr: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Detects a band of approximately 58 and 50 kDa corresponding to cytokeratins 5 and 14 respectively.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性
      Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
    • 细胞定位
      Cytoplasmic; Basal layer
    • 数据库链接
    • 别名
      • CK 14 antibody
      • CK 5 antibody
      • DDD antibody
      • k14 antibody
      • k5 antibody
      • Keratin 14 antibody
      • Keratin 5 antibody
      • Keratin type I cytoskeletal 14 antibody
      • Keratin type II cytoskeletal 5 antibody
      • krt14 antibody
      • krt5 antibody
      see all

    文献

    This product has been referenced in:
    • Arthur GK  et al. KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells. PLoS One 10:e0145259 (2015). Read more (PubMed: 26689552) »
    • Woodman LB  et al. Synthetic response of stimulated respiratory epithelium: modulation by prednisolone and iKK2 inhibition. Chest 143:1656-66 (2013). ICC/IF ; Human . Read more (PubMed: 23238614) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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