Anti-Cytokeratin 19抗体[RCK108], prediluted (ab49912)

概述

  • 产品名称Anti-Cytokeratin 19抗体[RCK108], prediluted
    参阅全部 Cytokeratin 19 一抗
  • 描述
    小鼠单克隆抗体[RCK108] to Cytokeratin 19, prediluted
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue/ cell preparation (Human), Cell line T24

  • 阳性对照
    • Glandular epithelia
  • 常规说明


    This antibody stains practically all epithelial tumours, especially adenocarcinoma. Staining is negative in hepatocellular carcinoma and also in most medullary and weakly differentiated ductal carcinomas.

性能

  • 形式Prediluted
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: Phosphate buffer, pH 7.3
  • Concentration information loading...
  • 纯度Tissue culture supernatant
  • Primary antibody说明This antibody stains practically all epithelial tumours, especially adenocarcinoma. Staining is negative in hepatocellular carcinoma and also in most medullary and weakly differentiated ductal carcinomas.
  • 克隆单克隆
  • 克隆编号RCK108
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab49912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Use Neat, 100µl per test.

WB Use at an assay dependent concentration. Detects a band of approximately 40 kDa (predicted molecular weight: 48 kDa).

靶标

  • 功能Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
  • 组织特异性Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
  • 序列相似性Belongs to the intermediate filament family.
  • 发展阶段Present in hair follicles at all stages of development.
  • 结构域This keratin differs from all other IF proteins in lacking the C-terminal tail domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 40 kDa keratin intermediate filament antibody
    • CK 19 antibody
    • CK-19 antibody
    • CK19 antibody
    • Cytokeratin 19 antibody
    • Cytokeratin-19 antibody
    • K19 antibody
    • K1C19_HUMAN antibody
    • K1CS antibody
    • Keratin 19 antibody
    • Keratin type I 40 kD antibody
    • Keratin type I 40kD antibody
    • Keratin type I cytoskeletal 19 antibody
    • Keratin, type I cytoskeletal 19 antibody
    • Keratin, type I, 40 kd antibody
    • Keratin-19 antibody
    • KRT19 antibody
    • MGC15366 antibody
    see all

Anti-Cytokeratin 19 antibody [RCK108], prediluted (ab49912)参考文献

ab49912 has not yet been referenced specifically in any publications.

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