Anti-Cytokeratin 19抗体(ab85351)


  • 产品名称Anti-Cytokeratin 19抗体
    参阅全部 Cytokeratin 19 一抗
  • 描述
    兔多克隆抗体to Cytokeratin 19
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Orangutan
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Cytokeratin 19.

    (Peptide available as ab94822.)

  • 阳性对照
    • This antibody gave a positive signal in Human skin tissue lysate and the following whole cell lysates: HepG2; MDA-MB-361



Our Abpromise guarantee covers the use of ab85351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
    • 组织特异性Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
    • 序列相似性Belongs to the intermediate filament family.
    • 发展阶段Present in hair follicles at all stages of development.
    • 结构域This keratin differs from all other IF proteins in lacking the C-terminal tail domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 40 kDa keratin intermediate filament antibody
      • CK 19 antibody
      • CK-19 antibody
      • CK19 antibody
      • Cytokeratin 19 antibody
      • Cytokeratin-19 antibody
      • K19 antibody
      • K1C19_HUMAN antibody
      • K1CS antibody
      • Keratin 19 antibody
      • Keratin type I 40 kD antibody
      • Keratin type I 40kD antibody
      • Keratin type I cytoskeletal 19 antibody
      • Keratin, type I cytoskeletal 19 antibody
      • Keratin, type I, 40 kd antibody
      • Keratin-19 antibody
      • KRT19 antibody
      • MGC15366 antibody
      see all

    Anti-Cytokeratin 19 antibody 图像

    • All lanes : Anti-Cytokeratin 19 antibody (ab85351) at 1 µg/ml

      Lane 1 : Human skin tissue lysate - total protein (ab30166)
      Lane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate
      Lane 3 : MDA-MB-361 (Human breast adenocarcinoma cell line) Whole Cell Lysate Whole Cell Lysate

      Lysates/proteins at 10 µg per lane.

      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 44 kDa
      Observed band size : 44 kDa
      Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 1 minute
    • Anti-Cytokeratin 19 antibody (ab85351) at 1 µg/ml + Recombinant Human Cytokeratin 19 protein (ab73639) at 0.01 µg

      Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
      developed using the ECL technique

      Performed under reducing conditions.

      Exposure time : 10 seconds

    Anti-Cytokeratin 19 antibody (ab85351)参考文献

    ab85351 has not yet been referenced specifically in any publications.

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