概述

  • 产品名称
    Anti-Cytokeratin 13抗体[2D7]
    参阅全部 Cytokeratin 13 一抗
  • 描述
    小鼠单克隆抗体[2D7] to Cytokeratin 13
  • 经测试应用
    适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mammal
  • 免疫原

    Cytokeratin preparation extracted from human esophagus

性能

应用

Our Abpromise guarantee covers the use of ab90096 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-Fr
  • 应用说明
    IHC-Fr: Recommended working dilution is 1:5-1:10.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 组织特异性
      Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
    • 疾病相关
      Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
    • 序列相似性
      Belongs to the intermediate filament family.
    • 翻译后修饰
      O-glycosylated; glycans consist of single N-acetylglucosamine residues.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 47 kDa cytokeratin antibody
      • CK-13 antibody
      • CK13 antibody
      • Cytokeratin 13 antibody
      • Cytokeratin-13 antibody
      • K13 antibody
      • K1C13_HUMAN antibody
      • Ka13 antibody
      • Keratin 13 antibody
      • Keratin antibody
      • keratin type I cytoskeletal 13 antibody
      • Keratin-13 antibody
      • Krt-1.13 antibody
      • Krt1-13 antibody
      • KRT13 antibody
      • MGC161462 antibody
      • MGC3781 antibody
      • type I cytoskeletal 13 antibody
      • Type I keratin Ka13 antibody
      • WSN2 antibody
      see all

    文献

    This product has been referenced in:
    • Rosekrans SL  et al. ER stress induces epithelial differentiation in the mouse oesophagus. Gut N/A:N/A (2014). Mouse . Read more (PubMed: 24789843) »
    • Kalabis J  et al. Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture. Nat Protoc 7:235-46 (2012). Read more (PubMed: 22240585) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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