Anti-Cytohesin 2抗体(ab65945)

概述

  • 产品名称Anti-Cytohesin 2抗体
    参阅全部 Cytohesin 2 一抗
  • 描述
    山羊多克隆抗体to Cytohesin 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse, Cow
  • 免疫原

    Synthetic peptide:

    EDGVYEPPDLTP

    , from the N-terminus of human Cytohesin 2

  • 阳性对照
    • Human cerebellum and rat brain lysates

性能

应用

Our Abpromise guarantee covers the use of ab65945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 46 kDa).

    Peptide ELISA: antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane.
    • 组织特异性Ubiquitous.
    • 序列相似性Contains 1 PH domain.
      Contains 1 SEC7 domain.
    • 结构域The PH domain is necessary and sufficient for plasma membrane relocalization.
    • 细胞定位Cell membrane. Cytoplasm. Both isoform 1 and isoform 2 are recruited to the cell membrane through its association with ARL4A, ARL4C and ARL4D. Requires also interaction with phosphoinositides for targeting to plasma membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ARF exchange factor antibody
      • ARF nucleotide binding site opener antibody
      • ARF nucleotide-binding site opener antibody
      • Arno antibody
      • ARNO protein antibody
      • CLM2 antibody
      • CTS18 antibody
      • CTS18.1 antibody
      • CYH2_HUMAN antibody
      • Cyth2 antibody
      • Cytohesin 2 antibody
      • Cytohesin-2 antibody
      • MGC137537 antibody
      • MGC80440 antibody
      • PH antibody
      • PH, SEC7 and coiled-coil domain-containing protein 2 antibody
      • Pleckstrin homology Sec7 and coiled coil domains 2 antibody
      • Pleckstrin homology Sec7 and coiled coil domains protein 2 antibody
      • Protein ARNO antibody
      • PSCD2 antibody
      • PSCD2L antibody
      • PSCD2L, formerly antibody
      • SEC7 and coiled-coil domain-containing protein 2 antibody
      • Sec7 antibody
      • SEC7 homolog B antibody
      • Sec7B antibody
      • SEC7L antibody
      • Sec7p L antibody
      • Sec7p-like antibody
      • Sec7pL antibody
      see all

    Anti-Cytohesin 2 antibody 图像

    Anti-Cytohesin 2 antibody (ab65945)参考文献

    ab65945 has not yet been referenced specifically in any publications.

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