概述

  • 产品名称Anti-Cytochrome P450 3A5抗体
    参阅全部 Cytochrome P450 3A5 一抗
  • 描述
    兔多克隆抗体to Cytochrome P450 3A5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    不与反应: Rat
  • 免疫原

    Synthetic hexapeptide including the C-terminal of human Cytochrome P450 3A5, conjugated to keyhole limpet haemocyanin using a maleimido linkage.

  • 阳性对照
    • Human liver microsomal preparations.

性能

应用

Our Abpromise guarantee covers the use of ab22692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/2000. Predicted molecular weight: 57 kDa.

    Note: dilute ab22692 to working concentration with 50mM Tris-HCl buffer (pH 7.6) containing 1.5% sodium chloride and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    • 序列相似性Belongs to the cytochrome P450 family.
    • 细胞定位Endoplasmic reticulum membrane. Microsome membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Aryl hydrocarbon hydroxylase antibody
      • CP35 antibody
      • CP3A5_HUMAN antibody
      • CYP3A5 antibody
      • CYPIIIA5 antibody
      • Cytochrome P450 3A5 antibody
      • Cytochrome P450 antibody
      • Cytochrome P450 family 3 subfamily A polypeptide 5 antibody
      • Cytochrome P450 HLp2 antibody
      • Cytochrome P450 subfamily IIIA (niphedipine oxidase) polypeptide 5 antibody
      • Cytochrome P450-PCN3 antibody
      • DKFZp686L16231 antibody
      • Flavoprotein linked monooxygenase antibody
      • FLJ31317 antibody
      • HLp2 antibody
      • Microsomal monooxygenase antibody
      • Niphedipine oxidase antibody
      • P450PCN3 antibody
      • PCN3 antibody
      • Xenobiotic monooxygenase antibody
      see all

    Anti-Cytochrome P450 3A5 antibody (ab22692)参考文献

    This product has been referenced in:
    • Leskelä S  et al. Cytochrome P450 3A5 is highly expressed in normal prostate cells but absent in prostate cancer. Endocr Relat Cancer 14:645-54 (2007). Read more (PubMed: 17914095) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"