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概述

  • 产品名称
    Anti-Cytochrome P450 2C23抗体
  • 描述
    兔多克隆抗体to Cytochrome P450 2C23
  • 特异性
    ab53944 is specific for Cytochrome P450 2C23.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Purified rat Cytochrome P450 2C23.

  • 阳性对照
    • Phenobarbital-treated liver microsome.

应用

Our Abpromise guarantee covers the use of ab53944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

靶标

  • 相关性
    The cytochrome P450 superfamily of heme-thiolate mono-oxygenases play a key role in the oxidative metabolism of many endogenous and exogenous molecules and are classified by their primary structure into four main groups. It is an ancient superfamily, which has been identified in prokaryotes and in many types of eukaryotic cells. Cytochrome P450 2 family, (CYP2) is the largest of the four groups, having five sub-families, 2A-2E. CYP2C23 was reported to efficiently catalyze arachidonic acid to epoxyeicosatrienoic acids (EETs) in rat kidney.
  • 细胞定位
    Endoplasmic reticulum membrane; Peripheral membrane protein.
  • 数据库链接
    • 别名
      • Arachidonic acid epoxygenase antibody
      • Cyp2c23 antibody
      • CYPIIC23 antibody

    Anti-Cytochrome P450 2C23 antibody 图像

    • Western blot - Cytochrome P450 2C23 antibody (ab53944)
      Western blot - Cytochrome P450 2C23 antibody (ab53944)
      All lanes : Anti-Cytochrome P450 2C23 antibody (ab53944) at 1/2000 dilution

      Lane 1 : Control liver microsome
      Lane 2 : Phenobarbital-treated liver microsome

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 56 kDa
      Observed band size : 56 kDa

    实验方案

    Anti-Cytochrome P450 2C23 antibody (ab53944)参考文献

    This product has been referenced in:
    • Caligiuri SP  et al. Dietary linoleic acid and a-linolenic acid differentially affect renal oxylipins and phospholipid fatty acids in diet-induced obese rats. J Nutr 143:1421-31 (2013). Read more (PubMed: 23902961) »
    • Mustafa S  et al. Renal expression of arachidonic acid metabolizing enzymes and RhoA/Rho kinases in fructose insulin resistant hypertensive rats. Mol Cell Biochem 333:203-9 (2010). WB ; Rat . Read more (PubMed: 19633817) »

    See all 2 Publications for this product

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