Anti-Cytochrome P450 2A6抗体(ab3570)

概述

  • 产品名称Anti-Cytochrome P450 2A6抗体
    参阅全部 Cytochrome P450 2A6 一抗
  • 描述
    兔多克隆抗体to Cytochrome P450 2A6
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Other Immunogen Type (His-tag) corresponding to Human Cytochrome P450 2A6. Purified, His-tagged, full length human P450 2A6 fusion protein.

  • 阳性对照
    • Rat liver lysate.

性能

应用

Our Abpromise guarantee covers the use of ab3570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
WB 1/2000. Detects a band of approximately 49 kDa (predicted molecular weight: 57 kDa).

This antibody detects an ~49 kDa protein representing P450 2A6 from rat liver extract.

靶标

  • 功能Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
  • 组织特异性Liver.
  • 序列相似性Belongs to the cytochrome P450 family.
  • 细胞定位Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Coumarin 7 hydroxylase antibody
    • Coumarin 7-hydroxylase antibody
    • CP2A6_HUMAN antibody
    • CPA6 antibody
    • CYP2A antibody
    • CYP2A3 antibody
    • CYP2A6 antibody
    • CYPIIA6 antibody
    • Cytochrome P450 2A6 antibody
    • Cytochrome P450 IIA3 antibody
    • Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6 antibody
    • Cytochrome P450(I) antibody
    • Cytochrome P450, family 2 subfamily A polypeptide 6 antibody
    • Flavoprotein linked monooxygenase antibody
    • P450C2A antibody
    • P450PB antibody
    • Xenobiotic monooxygenase antibody
    see all

Anti-Cytochrome P450 2A6 antibody 图像



  • Predicted band size : 57 kDa

    ab3570 at a dilution of 1/2000 staining cytochrome P450 2A6 in rat liver lysate by Western blot.

Anti-Cytochrome P450 2A6 antibody (ab3570)参考文献

ab3570 has not yet been referenced specifically in any publications.

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Thank you for your response. While I cannot retroactively apply a discount to the order you have placed, the code will entitle you to xx off of one primary antibody for a future purchase. The code must be used on or before 10 October 2012. I woul...

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Thank you for contacting us. The recommended dilution of 1:150 is a recommendation which we make to our customers based on our experiments or those of supplier, collaborator or customer input. Although we cannot know exactly why certain products req...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - whole (liver)
Loading amount 30 µg
Specification liver
Gel Running Conditions Reduced Denaturing (4-20% gel)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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提交于 Dec 13 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"