Anti-Cytochrome P450 1A1抗体(ab124295)

概述

  • 产品名称Anti-Cytochrome P450 1A1抗体
    参阅全部 Cytochrome P450 1A1 一抗
  • 描述
    兔多克隆抗体to Cytochrome P450 1A1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog, Pig, Chimpanzee, Macaque Monkey, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human Cytochrome P450 1A1.

  • 阳性对照
    • This antibody gave a positive signal in both Human Lung and Placenta tissue lysates.

性能

应用

Our Abpromise guarantee covers the use of ab124295 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 73 kDa (predicted molecular weight: 58 kDa).

靶标

  • 功能Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • 组织特异性Lung, lymphocytes and placenta.
  • 序列相似性Belongs to the cytochrome P450 family.
  • 细胞定位Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AHH antibody
    • AHRR antibody
    • Aryl hydrocarbon hydroxylase antibody
    • CP11 antibody
    • CP1A1_HUMAN antibody
    • CYP 1 antibody
    • CYP1 antibody
    • cyp1a1 antibody
    • CYPIA1 antibody
    • Cytochrome P1 450 dioxin inducible antibody
    • Cytochrome P1-450 antibody
    • Cytochrome P450 1A1 antibody
    • Cytochrome P450 family 1 subfamily A polypeptide 1 antibody
    • Cytochrome P450 form 6 antibody
    • Cytochrome P450 subfamily I (aromatic compound inducible) polypeptide 1 antibody
    • Cytochrome P450-C antibody
    • Cytochrome P450-P1 antibody
    • Flavoprotein-linked monooxygenase antibody
    • Microsomal monooxygenase antibody
    • P1 450 antibody
    • P450 C antibody
    • P450 form 6 antibody
    • P450 P1 antibody
    • P450DX antibody
    • Xenobiotic monooxygenase antibody
    see all

Anti-Cytochrome P450 1A1 antibody 图像

  • All lanes : Anti-Cytochrome P450 1A1 antibody (ab124295) at 1 µg/ml

    Lane 1 : Lung (Human) Tissue Lysate
    Lane 2 : Human placenta tissue lysate - total protein (ab29745)
    Lane 3 : Lung (Human) Tissue Lysate with Immunising peptide at 1 µg/ml
    Lane 4 : Human placenta tissue lysate - total protein (ab29745) with Immunising peptide at 1 µg/ml

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 58 kDa
    Observed band size : 73 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 48 kDa,55 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 90 seconds

Anti-Cytochrome P450 1A1 antibody (ab124295)参考文献

ab124295 has not yet been referenced specifically in any publications.

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