Anti-Cytochrome C Oxidase subunit VIb抗体(ab54575)


  • 产品名称Anti-Cytochrome C Oxidase subunit VIb抗体
    参阅全部 Cytochrome C Oxidase subunit VIb 一抗
  • 描述
    小鼠单克隆抗体to Cytochrome C Oxidase subunit VIb
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: MAEDMETKIK NYKTAPFDSR FPNQNQTRNC WQNYLDFHRC QKAMTAKGGD ISVCEWYQRV YQSLCPTSWV TDWDEQRAEG TFPGKI, corresponding to amino acids 1-87 of Human Cytochrome C Oxidase subunit VIb


Our Abpromise guarantee covers the use of ab54575 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 10 kDa.
IHC-P Use a concentration of 0.3 µg/ml.


  • 功能Connects the two COX monomers into the physiological dimeric form.
  • 疾病相关Defects in COX6B1 are a cause of mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]; also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome.
  • 序列相似性Belongs to the cytochrome c oxidase subunit 6B family.
  • 细胞定位Mitochondrion intermembrane space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • COX 6B antibody
    • COX VIb 1 antibody
    • COX VIb-1 antibody
    • COX6B antibody
    • COX6B1 antibody
    • COXG antibody
    • COXVIb1 antibody
    • CX6B1_HUMAN antibody
    • Cytochrome c oxidase subunit 6B1 antibody
    • Cytochrome c oxidase subunit VIb antibody
    • Cytochrome c oxidase subunit VIb isoform 1 antibody
    • cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) antibody
    • Cytochrome c oxidase subunit Vib polypeptide 1 antibody
    see all

Anti-Cytochrome C Oxidase subunit VIb antibody 图像

  • Predicted band size : 10 kDa
    Cytochrome C Oxidase subunit VIb antibody (ab54575) at 1ug/lane + HL-60 cell lysate at 25ug/lane.
  • ab54575 at 0.3 µg/ml staining Cytochrome C Oxidase subunit VIb in human kidney tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

Anti-Cytochrome C Oxidase subunit VIb antibody (ab54575)参考文献

This product has been referenced in:
  • Nuss JE  et al. Multi-Faceted Proteomic Characterization of Host Protein Complement of Rift Valley Fever Virus Virions and Identification of Specific Heat Shock Proteins, Including HSP90, as Important Viral Host Factors. PLoS One 9:e93483 (2014). WB . Read more (PubMed: 24809507) »

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