概述

  • 产品名称
    Anti-Cystatin C抗体
    参阅全部 Cystatin C 一抗
  • 描述
    山羊多克隆抗体to Cystatin C
  • 经测试应用
    适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein purified from Human urine.

  • 阳性对照
    • Human kidney tubules tissue.

性能

应用

Our Abpromise guarantee covers the use of ab117642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能
    As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
  • 组织特异性
    Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
  • 疾病相关
    Amyloidosis 6
    Macular degeneration, age-related, 11
  • 序列相似性
    Belongs to the cystatin family.
  • 翻译后修饰
    The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AD 8 antibody
    • AD8 antibody
    • Amyloid angiopathy and cerebral hemorrhage antibody
    • ARMD11 antibody
    • bA218C14.4 (cystatin C) antibody
    • bA218C14.4 antibody
    • Cst 3 antibody
    • Cst3 antibody
    • CST3 protein antibody
    • Cystatin 3 antibody
    • Cystatin-3 antibody
    • Cystatin-C antibody
    • Cystatin3 antibody
    • CystatinC antibody
    • CYTC_HUMAN antibody
    • Epididymis secretory protein Li 2 antibody
    • Gamma trace antibody
    • Gamma-trace antibody
    • HCCAA antibody
    • HEL S 2 antibody
    • MGC117328 antibody
    • Neuroendocrine basic polypeptide antibody
    • Post gamma globulin antibody
    • Post-gamma-globulin antibody
    see all

图片

  • Human Kidney, Tubules, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117642 at 5µg/ml.

文献

This product has been referenced in:
  • Prozialeck WC  et al. Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat. Biometals 29:131-46 (2016). Read more (PubMed: 26715107) »

See 1 Publication for this product

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