概述

  • 产品名称Anti-CYP4V2抗体
    参阅全部 CYP4V2 一抗
  • 描述
    小鼠多克隆抗体to CYP4V2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human protein, CYP4V2 (NP_997235).

  • 阳性对照
    • CYP4V2 transfected 293T cell lysate; human liver lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).

靶标

  • 功能Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12). May have a role in fatty acid and steroid metabolism in the eye.
  • 组织特异性Broadly expressed. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, retina, retinal pigment epithelium (RPE) and lymphocytes.
  • 疾病相关Bietti crystalline corneoretinal dystrophy (BCD) [MIM:210370]: An autosomal recessive ocular disease characterized by retinal degeneration and marginal corneal dystrophy. Typical features include multiple glistening intraretinal crystals scattered over the fundus, a characteristic degeneration of the retina, and sclerosis of the choroidal vessels, ultimately resulting in progressive night blindness and constriction of the visual field. Most patients have similar crystals at the corneoscleral limbus. Patients develop decreased vision, nyctalopia, and paracentral scotomata between the 2nd and 4th decade of life. Later, they develop peripheral visual field loss and marked visual impairment, usually progressing to legal blindness by the 5th or 6th decade of life. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 序列相似性Belongs to the cytochrome P450 family.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BCD antibody
    • CP4V2_HUMAN antibody
    • CYP4AH1 antibody
    • CYP4V 2 antibody
    • CYP4V2 antibody
    • Cytochrome P450 4V2 antibody
    • Cytochrome P450, family 4, subfamily V, polypeptide 2 antibody
    • Retina CYP4V2 antibody
    see all

Anti-CYP4V2 antibody 图像

  • All lanes : Anti-CYP4V2 antibody (ab69392) at 1/500 dilution

    Lane 1 : CYP4V2 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 61 kDa
    Observed band size : 61 kDa
  • Anti-CYP4V2 antibody (ab69392) at 1/500 dilution + human liver lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 61 kDa
    Observed band size : 61 kDa

Anti-CYP4V2 antibody (ab69392)参考文献

ab69392 has not yet been referenced specifically in any publications.

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