Anti-CYP2R1抗体(ab79924)

概述

  • 产品名称Anti-CYP2R1抗体
    参阅全部 CYP2R1 一抗
  • 描述
    兔多克隆抗体to CYP2R1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide within Human CYP2R1 aa 152-180 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.

  • 阳性对照
    • NCI-H460 cell lysate Mouse liver tissue lysate

应用

Our Abpromise guarantee covers the use of ab79924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).

靶标

  • 功能Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3).
  • 疾病相关Defects in CYP2R1 are the cause of rickets vitamin D-dependent type 1B (VDDR1B) [MIM:600081]; also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. A disorder caused by a selective deficiency of the active form of vitamin D (1,25-dihydroxyvitamin D3) and resulting in defective bone mineralization and clinical features of rickets. The patients sera have low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activityand low levels of 25-hydroxyvitamin D.
  • 序列相似性Belongs to the cytochrome P450 family.
  • 细胞定位Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CP2R1_HUMAN antibody
    • CYP2R1 antibody
    • Cytochrome P450 2R1 antibody
    • Cytochrome P450 family 2 R1 antibody
    • Cytochrome P450 family 2 subfamily R polypeptide 1 antibody
    • EC 1.14.13.15 antibody
    • MGC4663 antibody
    • Vitamin D 25 hydroxylase antibody
    • Vitamin D 25-hydroxylase antibody
    see all

Anti-CYP2R1 antibody 图像

  • Anti-CYP2R1 antibody (ab79924) at 1/50 dilution + NCI-H460 cell lysate at 35 µg

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
  • Anti-CYP2R1 antibody (ab79924) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 57 kDa
    Observed band size : 57 kDa

Anti-CYP2R1 antibody (ab79924)参考文献

ab79924 has not yet been referenced specifically in any publications.

Product Wall

This CYP2R1 antibody is generated from rabbits immunized with a KLH-conjugated synthetic peptide between 152-180 amino acids from the Central region of human CYP2R1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"