Anti-CYP2C8抗体(ab88904)

概述

  • 产品名称Anti-CYP2C8抗体
    参阅全部 CYP2C8 一抗
  • 描述
    小鼠多克隆抗体to CYP2C8
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human CYP2C8 (AAH20596.1, amino acids 1-490)

  • 阳性对照
    • Human liver tissue lysate; CYP2C8 transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab88904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.

靶标

  • 功能Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).
  • 序列相似性Belongs to the cytochrome P450 family.
  • 细胞定位Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CP2C8_HUMAN antibody
    • CPC8 antibody
    • CYP2C8 antibody
    • CYPIIC8 antibody
    • Cytochrome P450 2C8 antibody
    • Cytochrome P450 family 2 subfamily C polypeptide 8 antibody
    • Cytochrome P450 form 1 antibody
    • Cytochrome P450 IIC2 antibody
    • Cytochrome P450 MP-12 antibody
    • Cytochrome P450 MP-20 antibody
    • Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 8 antibody
    • Flavoprotein linked monooxygenase antibody
    • Microsomal monooxygenase antibody
    • MP 12/MP 20 antibody
    • P450 form 1 antibody
    • P450 IIC2 antibody
    • P450 MP 12/MP 20 antibody
    • S mephenytoin 4 hydroxylase antibody
    • S-mephenytoin 4-hydroxylase antibody
    • Xenobiotic monooxygenase antibody
    see all

Anti-CYP2C8 antibody 图像

  • Anti-CYP2C8 antibody (ab88904) at 1/500 dilution + human liver tissue lysate at 50 µg

    Predicted band size : 56 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-CYP2C8 antibody (ab88904) at 1/500 dilution

    Lane 1 : CYP2C8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 56 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)

Anti-CYP2C8 antibody (ab88904)参考文献

ab88904 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for your call today and for letting us know about the trouble with this antibody.

As we discussed, I'm sending a free of charge vial of ab126844 on the order ****. Please keep me updated about the results with this replace...

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Here is the peptide immunogeninformation for ab126844:

Synthetic peptide: KNVALTRSYIREK (Human) by a Cysteine residue linker from the internal region of Human CYP2C8 (NP_000761.3; NP_001185782.1; NP_00118...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"