Mouse, Rat, Pig
Recombinant fragment, corresponding to a sequence within amino acids 241-498 of Human CYP24A1 (NP_000773).
293T, A431, H1299, HeLaS3, HepG2, Molt4 and Raji whole cell lysates.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 59 kDa.
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Belongs to the cytochrome P450 family.
Information by UniProt
1 25 @dihydroxyvitamin D3 24 hydroxylase antibody
1 25 dihydroxyvitamin D(3) 24 hydroxylase antibody
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