概述

  • 产品名称Anti-CYP24A1抗体
    参阅全部 CYP24A1 一抗
  • 描述
    兔多克隆抗体to CYP24A1
  • 特异性Detects endogenous levels of total CYP24A1 protein.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from internal sequence of human CYP24A1.

  • 阳性对照
    • Extracts from HUVEC cells

应用

Our Abpromise guarantee covers the use of ab65956 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: 1/10000.
    WB: 1/500 - 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 59 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
    • 序列相似性Belongs to the cytochrome P450 family.
    • 细胞定位Mitochondrion.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 1 25 @dihydroxyvitamin D3 24 hydroxylase antibody
      • 1 25 dihydroxyvitamin D(3) 24 hydroxylase antibody
      • 1 antibody
      • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial antibody
      • 24 OHase antibody
      • 24-OHase antibody
      • 25-dihydroxyvitamin D(3) 24-hydroxylase antibody
      • CP 24 antibody
      • CP24 antibody
      • CP24A_HUMAN antibody
      • CYP 24 antibody
      • CYP24 antibody
      • CYP24A1 antibody
      • Cytochrome P450 24A1 antibody
      • Cytochrome P450 24A1 mitochondrial antibody
      • cytochrome P450 CC24 antibody
      • Cytochrome P450 family 24 antibody
      • Cytochrome P450 family 24 subfamily A polypeptide 1 antibody
      • Cytochrome P450 subfamily XXIV antibody
      • Cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) antibody
      • Cytochrome P450-CC24 antibody
      • EC 1.14.13.n4 antibody
      • Exo mitochondrial protein antibody
      • HCAI antibody
      • MGC126273 antibody
      • MGC126274 antibody
      • mitochondrial antibody
      • P450 CC24 antibody
      • Vitamin D 24 hydroxylase antibody
      • Vitamin D(3) 24 hydroxylase antibody
      • Vitamin D(3) 24-hydroxylase antibody
      see all

    Anti-CYP24A1 antibody 图像

    • All lanes : Anti-CYP24A1 antibody (ab65956) at 1/500 dilution

      Lane 1 : extracts from HUVEC cells
      Lane 2 : extracts from HUVEC cells with immunizing peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 59 kDa
      Observed band size : 36 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 33 kDa. We are unsure as to the identity of these extra bands.

    Anti-CYP24A1 antibody (ab65956)参考文献

    ab65956 has not yet been referenced specifically in any publications.

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