Anti-CYP24A1抗体(ab54594)

概述

  • 产品名称Anti-CYP24A1抗体
    参阅全部 CYP24A1 一抗
  • 描述
    小鼠单克隆抗体to CYP24A1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Human
  • 免疫原

    Recombinant fragment: LMLNTQVLGS SEDNFEDSSQ FRPERWLQEK EKINPFAHLP FGVGKRMCIG RRLAELQLHL ALCWIVRKYD IQATDNEPVE MLHSGTLVPS RELPIAFCQR , corresponding to amino acids 415-515 of Human CYP24A1

应用

Our Abpromise guarantee covers the use of ab54594 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

靶标

  • 功能Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
  • 序列相似性Belongs to the cytochrome P450 family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1 25 @dihydroxyvitamin D3 24 hydroxylase antibody
    • 1 25 dihydroxyvitamin D(3) 24 hydroxylase antibody
    • 1 antibody
    • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial antibody
    • 24 OHase antibody
    • 24-OHase antibody
    • 25-dihydroxyvitamin D(3) 24-hydroxylase antibody
    • CP 24 antibody
    • CP24 antibody
    • CP24A_HUMAN antibody
    • CYP 24 antibody
    • CYP24 antibody
    • CYP24A1 antibody
    • Cytochrome P450 24A1 antibody
    • Cytochrome P450 24A1 mitochondrial antibody
    • cytochrome P450 CC24 antibody
    • Cytochrome P450 family 24 antibody
    • Cytochrome P450 family 24 subfamily A polypeptide 1 antibody
    • Cytochrome P450 subfamily XXIV antibody
    • Cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) antibody
    • Cytochrome P450-CC24 antibody
    • EC 1.14.13.n4 antibody
    • Exo mitochondrial protein antibody
    • HCAI antibody
    • MGC126273 antibody
    • MGC126274 antibody
    • mitochondrial antibody
    • P450 CC24 antibody
    • Vitamin D 24 hydroxylase antibody
    • Vitamin D(3) 24 hydroxylase antibody
    • Vitamin D(3) 24-hydroxylase antibody
    see all

Anti-CYP24A1 antibody 图像

  • Western blot against tagged recombinant protein immunogen using ab54594 CYP24A1 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Anti-CYP24A1 antibody (ab54594)参考文献

ab54594 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 30 µg
Gel Running Conditions Reduced Denaturing
Sample Human Cell lysate - whole cell (vascular smooth muscle cell)
Specification vascular smooth muscle cell
Blocking step Milk as blocking agent for 3 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C
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提交于 Mar 26 2015

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