This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

概述

  • 产品名称Anti-CYFIP1抗体
    参阅全部 CYFIP1 一抗
  • 描述
    山羊多克隆抗体to CYFIP1

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • 特异性Expected to recognize isoform a only (NP_055423.1).
  • 种属反应性

    预测可用于: Mouse, Rat, Human, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide: C-

    TGSGRQEAQKTDAE

    , corresponding to internal amino acids 373 - 386 of Human CYFIP1 (NP_055423.1)

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG

靶标

  • 功能Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.
  • 序列相似性Belongs to the CYFIP family.
  • 细胞定位Cytoplasm > perinuclear region. Cell projection > lamellipodium. Cell projection > ruffle. Cell junction > synapse > synaptosome. Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CY antibody
    • CYFIP 1 antibody
    • CYFIP1 antibody
    • CYFP1_HUMAN antibody
    • Cytoplasmic FMR1 interacting protein 1 antibody
    • Cytoplasmic FMR1-interacting protein 1 antibody
    • FLJ45151 antibody
    • KIAA0068 antibody
    • p140sra 1 antibody
    • p140sra-1 antibody
    • P140SRA1 antibody
    • Selective hybridizing clone antibody
    • SHYC antibody
    • Specifically Rac1 associated protein 1 antibody
    • Specifically Rac1-associated protein 1 antibody
    • SRA 1 antibody
    • Sra-1 antibody
    • SRA1 antibody
    see all

Anti-CYFIP1 antibody (ab99460)参考文献

ab99460 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab99460.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"