重组
RabMAb

Anti-Cyclin H抗体[EPR3928] (ab111933)

概述

  • 产品名称
    Anti-Cyclin H抗体[EPR3928]
    参阅全部 Cyclin H 一抗
  • 描述
    兔单克隆抗体[EPR3928] to Cyclin H
  • 经测试应用
    适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide, corresponding to residues from Human Cyclin H.

  • 阳性对照
    • Jurkat, A431, K562 and HeLa cell lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

应用

Our Abpromise guarantee covers the use of ab111933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 38 kDa.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能
      Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
    • 序列相似性
      Belongs to the cyclin family. Cyclin C subfamily.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 6330408H09Rik antibody
      • AI661354 antibody
      • AV102684 antibody
      • AW538719 antibody
      • CAK antibody
      • CAK complex subunit antibody
      • ccnh antibody
      • CCNH_HUMAN antibody
      • CDK activating kinase antibody
      • CDK activating kinase complex subunit antibody
      • Cyclin dependent kinase activating kinase antibody
      • cyclin dependent kinase activating kinase complex subunit antibody
      • Cyclin H antibody
      • Cyclin-H antibody
      • CyclinH antibody
      • MO15 associated protein antibody
      • MO15-associated protein antibody
      • p34 antibody
      • p36 antibody
      • p37 antibody
      see all

    图片

    • All lanes : Anti-Cyclin H antibody [EPR3928] (ab111933) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : A431 cell lsyate
      Lane 3 : K562 cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 38 kDa

    实验方案

    文献

    ab111933 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab111933.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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