Anti-Cyclin G抗体[11C8] (ab49274)

概述

  • 产品名称Anti-Cyclin G抗体[11C8]
    参阅全部 Cyclin G 一抗
  • 描述
    小鼠单克隆抗体[11C8] to Cyclin G
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment:Prokaryotic recombinant protein corresponding to 142 amino acids of the C terminal region of (human) cyclin G1.

  • 阳性对照
    • Immunohistochemistry: Tonsil. Western Blotting: MCF7 cell line.

性能

应用

Our Abpromise guarantee covers the use of ab49274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明IHC-P: 1/20 - 1/40. High temperature antigen unmasking technique. 60 minutes primary antibody incubation at 25oC and standard ABC technique are recommended.
    WB: 1/100 - 1/250. Predicted molecular weight: 34 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
    • 组织特异性High levels in skeletal muscle, ovary, kidney and colon.
    • 序列相似性Belongs to the cyclin family. Cyclin G subfamily.
    • 发展阶段Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.
    • 细胞定位Nucleus. DNA replication foci after DNA damage.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CCNG 1 antibody
      • CCNG antibody
      • CCNG1 antibody
      • CCNG1_HUMAN antibody
      • CYCG1 antibody
      • Cyclin G antibody
      • Cyclin G1 antibody
      • Cyclin-G antibody
      • Cyclin-G1 antibody
      see all

    Anti-Cyclin G antibody [11C8] (ab49274)参考文献

    ab49274 has not yet been referenced specifically in any publications.

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