存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: None
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纯度 IgG fraction
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Predicted molecular weight: 58 kDa.
功能 Essential for the control of the cell cycle at the G2/M (mitosis) transition.
序列相似性 Belongs to the cyclin family. Cyclin AB subfamily.
发展阶段 Accumulates steadily during G2 and is abruptly destroyed at mitosis.
翻译后修饰 Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.
细胞定位 Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.
Information by UniProt
CCNB 1 antibody
Anti-Cyclin B1 antibody [V143.1] (ab18219)参考文献
This product has been referenced in:
et al. OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression. Mol Cell Biol 36:2568-82 (2016).
Read more (PubMed: 27481995) »
et al. Female infertility in PDE3A (-/-) mice: Polo-like kinase 1 (Plk1) may be a target of Protein Kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A (-/- ) mice. Cell Cycle 9:4720-34 (2010).
Read more (PubMed: 21099356) »
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for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"