Anti-CXCR2抗体[MM0222-7J40] (ab89254)
Key features and details
- Mouse monoclonal [MM0222-7J40] to CXCR2
- Suitable for: IHC-Fr, Flow Cyt, WB, Neutralising
- Reacts with: Human
- Isotype: IgG2a
概述
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产品名称
Anti-CXCR2抗体[MM0222-7J40]
参阅全部 CXCR2 一抗 -
描述
小鼠单克隆抗体[MM0222-7J40] to CXCR2 -
宿主
Mouse -
经测试应用
适用于: IHC-Fr, Flow Cyt, WB, Neutralisingmore details -
种属反应性
与反应: Human -
免疫原
Human recombinant CXCR2
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阳性对照
- WB: Human placenta tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography. -
克隆
单克隆 -
克隆编号
MM0222-7J40 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab89254于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-Fr |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
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WB |
1/500 - 1/1000. Predicted molecular weight: 40 kDa.
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Neutralising |
Use at an assay dependent concentration.
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说明 |
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IHC-Fr
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. |
WB
1/500 - 1/1000. Predicted molecular weight: 40 kDa. |
Neutralising
Use at an assay dependent concentration. |
靶标
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功能
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
翻译后修饰
Phosphorylated upon ligand binding; which is required for desensitization. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 3579 Human
- Omim: 146928 Human
- SwissProt: P25025 Human
- Unigene: 846 Human
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别名
- C-X-C chemokine receptor type 2 antibody
- CD 182 antibody
- CD182 antibody
see all
图片
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Anti-CXCR2 antibody [MM0222-7J40] (ab89254) at 1/500 dilution + Human placenta tissue lysate
Predicted band size: 40 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
实验方案
数据表及文件
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Datasheet download
文献 (1)
ab89254 被引用在 1 文献中.
- Strong MJ et al. Dura promotes metastatic potential in prostate cancer through the CXCR2 pathway. J Neurooncol 153:33-42 (2021). PubMed: 33835371