Anti-CXCL2抗体(ab91511)
Key features and details
- Goat polyclonal to CXCL2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CXCL2抗体
参阅全部 CXCL2 一抗 -
描述
山羊多克隆抗体to CXCL2 -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Cynomolgus monkey -
免疫原
Synthetic peptide corresponding to Human CXCL2 aa 94-107 (C terminal). Synthetic peptide:
C-KKIIEKMLKNGKSN
, corresponding to C terminal amino acids 94-107 of Human GRO beta (NP_002080.1).
Sequence:C-KKIIEKMLKNGKSN
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阳性对照
- Recombinant Human CXCL2 protein (ab84204) can be used as a positive control in WB. Human duodenum lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab91511 was purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab91511于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 11 kDa).
1 hour primary incubation is recommended for this product. |
说明 |
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WB
Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 11 kDa). 1 hour primary incubation is recommended for this product. |
靶标
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功能
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. -
序列相似性
Belongs to the intercrine alpha (chemokine CxC) family. -
翻译后修饰
The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 2920 Human
- Omim: 139110 Human
- SwissProt: P19875 Human
- Unigene: 75765 Human
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别名
- C-X-C motif chemokine 2 antibody
- Chemokine (C X C motif) ligand 2 antibody
- Chemokine, CXC motif, ligand 2 antibody
see all
图片
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Anti-CXCL2 antibody (ab91511) at 0.2 µg/ml + Human duodenum lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 11 kDa
Observed band size: 17 kDa why is the actual band size different from the predicted?
Exposure time: 1 hour -
ab91511 (0.03µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
数据表及文件
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Datasheet download
文献 (6)
ab91511 被引用在 6 文献中.
- Kim J et al. Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood. NPJ Genom Med 6:87 (2021). PubMed: 34654834
- Yang J et al. Characteristics of CXCL2 expression in coronary atherosclerosis and negative regulation by microRNA-421. J Int Med Res 48:300060519896150 (2020). PubMed: 32212883
- Wilkinson HN et al. Elevated Local Senescence in Diabetic Wound Healing Is Linked to Pathological Repair via CXCR2. J Invest Dermatol 139:1171-1181.e6 (2019). PubMed: 30684552
- Wan XY et al. Antimetastatic effects of norcantharidin on hepatocellular carcinoma cells by up-regulating FAM46C expression. Am J Transl Res 9:155-166 (2017). WB ; Human . PubMed: 28123642
- Buoli Comani G et al. miRNA-regulated gene expression differs in celiac disease patients according to the age of presentation. Genes Nutr 10:482 (2015). PubMed: 26233308
- Magni S et al. miRNAs Affect the Expression of Innate and Adaptive Immunity Proteins in Celiac Disease. Am J Gastroenterol N/A:N/A (2014). PubMed: 25070052