The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明 ELISA: Use at a concentration of 0.15 - 0.3 µg/ml. Allows the detection of at least 0.2 ng/well of recombinant human CXCL16.
WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant human CXCL16 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. Predicted molecular weight: 33 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
组织特异性Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
序列相似性Belongs to the intercrine alpha (chemokine CxC) family.
细胞定位Cell membrane. Secreted. Also exists as a soluble form.