Highly pure (>98%) recombinant full length Mouse CXCL16.
形式Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary
存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Constituents: PBS, pH 7.2
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纯度Immunogen affinity purified
纯化说明ab84435 is purified by affinity chromatography employing immobilized CXCL16 matrix and filter sterilised.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 27 kDa. Detection limit for recombinant mouse CXCL16 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Use a concentration of 0.5 - 2 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant mouse CXCL16.
Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Goat polyclonal to CXCL16 (Biotin) (ab84434). Can be used as capture antibody with related pair. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant mouse CXCL16.
功能Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
组织特异性Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
序列相似性Belongs to the intercrine alpha (chemokine CxC) family.
细胞定位Cell membrane. Secreted. Also exists as a soluble form.