概述

  • 产品名称Anti-CXCL16抗体
    参阅全部 CXCL16 一抗
  • 描述
    兔多克隆抗体to CXCL16
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 52-193 of Human CXCL16 (AAH17588).

  • 阳性对照
    • A549, HepG2 whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab101404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.
IHC-P 1/100 - 1/500. Antigen retrieval is recommended using heat mediated 10mM Citrate buffer or Tris-EDTA buffer (pH: 8.0)

靶标

  • 功能Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
  • 组织特异性Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
  • 序列相似性Belongs to the intercrine alpha (chemokine CxC) family.
  • 翻译后修饰Glycosylated.
  • 细胞定位Cell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C-X-C motif chemokine 16 antibody
    • Chemokine (C X C motif) ligand 16 antibody
    • Chemokine, CXC motif, ligand 16 antibody
    • CXC chemokine ligand 16 antibody
    • Cxcl16 antibody
    • CXCLG16 antibody
    • CXL16_HUMAN antibody
    • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibody
    • SCYB16 antibody
    • Small inducible cytokine B16 precursor antibody
    • Small-inducible cytokine B16 antibody
    • SR-PSOX antibody
    • SRPSOX antibody
    • Transmembrane chemokine CXCL16 antibody
    • UNQ2759/PRO6714 antibody
    see all

Anti-CXCL16 antibody 图像

  • Anti-CXCL16 antibody (ab101404) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 28 kDa
  • Immunohistochemical analysis of paraffin-embedded H661 xenograft, using ab101404 at 1/100 dilution.

Anti-CXCL16 antibody (ab101404)参考文献

This product has been referenced in:
  • Ali-Rahmani F  et al. C282Y-HFE gene variant affects cholesterol metabolism in human neuroblastoma cells. PLoS One 9:e88724 (2014). WB ; Human . Read more (PubMed: 24533143) »
  • Voloshyna I  et al. Plasma from rheumatoid arthritis patients promotes pro-atherogenic cholesterol transport gene expression in THP-1 human macrophages. Exp Biol Med (Maywood) 238:1192-7 (2013). WB ; Human . Read more (PubMed: 24000379) »

See all 2 Publications for this product

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