概述

  • 产品名称
  • 描述
    兔多克隆抗体to CX3CR1
  • 特异性
    Recombinant and natural rat CX3CR1
  • 经测试应用
    适用于: IHC-P, IHC-Fr, WB, IP, Neutralisingmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Recombinant amino terminal fragment (Rat).

性能

应用

Our Abpromise guarantee covers the use of ab7200 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500.
IHC-Fr 1/100 - 1/500.
WB 1/1000 - 1/2000.
IP 1/300 - 1/800.
Neutralising Use at an assay dependent concentration.

靶标

  • 功能
    Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
  • 组织特异性
    Expressed in lymphoid and neural tissues.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta chemokine receptor-like 1 antibody
    • C X3 C CKR 1 antibody
    • C-X3-C CKR-1 antibody
    • CCRL1 antibody
    • Chemokine C X3 C motif receptor 1 antibody
    • CMK BRL 1 antibody
    • CMK-BRL-1 antibody
    • CMK-BRL1 antibody
    • CMKBLR1 antibody
    • CMKDR1 antibody
    • CX3C chemokine receptor 1 antibody
    • CX3C CKR1 antibody
    • CX3C1_HUMAN antibody
    • CX3CR1 antibody
    • Fractalkine receptor antibody
    • G-protein coupled receptor 13 antibody
    • GPR13 antibody
    • GPRV28 antibody
    • V28 antibody
    see all

文献

This product has been referenced in:
  • Gazerani S  et al. The Role of C Fibers in Spinal Microglia Induction and Possible Relation with TRPV3 Expression During Chronic Inflammatory Arthritis in Rats. Basic Clin Neurosci 7:231-40 (2016). Rat . Read more (PubMed: 27563416) »
  • Slusarczyk J  et al. Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress. Neural Plast 2016:7258201 (2016). WB . Read more (PubMed: 27239349) »

See all 5 Publications for this product

客户评价及客户问答

Thank you for your enquiry and your interest in our products. All of these 4 antibodies (ab8021, ab7200, ab7201, ab51668) recognize CX3CR1 and are suitable for Western blot application. However, ab7200 has been tested and characterized for detecting ra...

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Thank you for your enquiry. Yes, you are correct we have received a favourable Abreview using this antibody by western blotting where the antibody was diluted 1:1500 in 5% non-fat milk/PBST and the blots were labelled for two hours. This is supporte...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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